EGFR co-inhibition in KRAS

Megan Barnet, Medical Oncologist at The Kinghorn Cancer Centre, shared on X:

“Great summary from Ryan Corcoran (Mass General Cancer Center) re targeting RAS. Similar single agent ORR G12Cinh PDAC compared with NSCLC, vs CRC which improves with addition anti-EGFR. Supports KRAS good target in PDAC …just need to progress in G12D.”