Praveen Kumar Marimuthu, DM Resident in Medical Oncology at Christian Medical College and Hospital, shared an article by Andrea Cercek, et al. on X:
“Nonoperative Rx of d-MMR tumors NEJM:
Neoadjuvant dostarlimab (500 mg q3w x 6 mo) for Stage I–III dMMR solid tumors (rectal and non-rectal):
- 4/5 had cCR.
- 4/5 avoided surgery.
- 2-yr RFS 92%.
- No Rx-related deaths.
For prostate, GE.”
Nonoperative Management of Mismatch Repair–Deficient Tumors.
Journal: The New England Journal of Medicine
Authors: Andrea Cercek, et al.
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