Robert Orlowski, Deputy Chair of Lymphoma/Myeloma, Vice Chair of MM Research, and Florence Maude Thomas Cancer Research Professor at the University of Texas MD Anderson Cancer Center, shared a post on X:
“Myeloma Paper of the Day:
Endogenous T cell landscape is reshaped by CAR-T with a novel transitional CD8+ T cell population predicting poor outcomes, while targeting TIM3/GAL9 interactions may mitigate T cell exhaustion, apoptosis, and low persistence.”
Title: The endogenous T cell landscape is reshaped by CAR-T cell therapy and predicts treatment response in multiple myeloma
Authors: Julia Frede, Julia C. Poller, Kayleen Shi, Hannah Stuart, Noori Sotudeh, Claire Havig, Klothilda Lim, Caroline R. M. Wiggers, Eugene Y. Cho, Tushara Vijaykumar, Jianlin Liu, Johannes M. Waldschmidt, Monica S. Nair, Praveen Anand, Valeriya Dimitrova, Anna Montanaro, Andrew J. Yee, Nikhil C. Munshi, Kenneth C. Anderson, Nathan Martin, Shari M. Kaiser, Marc-Steffen Raab, Noopur S. Raje, Birgit Knoechel, Jens G. Lohr
You can read the Full Article in Leukemia.
You can find more posts featuring Robert Orlowski on OncoDaily.
