Robert Orlowski, Deputy Chair of Lymphoma/Myeloma, Vice Chair of MM Research, and Florence Maude Thomas Cancer Research Professor at the University of Texas MD Anderson Cancer Center, shared a post on X:
“Myeloma Paper of the Day:
Myeloma-associated long non-coding RNA PLUM (overexpressed in NF-ĸB mutant high-risk subtypes) confers chemoresistance by enhancing PRC2-mediated UPR activation, and targeting PLUM-EZH2 interactions may be a potent strategy.”
Title: Multiple myeloma-associated long non-coding RNA PLUM confers chemoresistance by enhancing PRC2-mediated UPR pathway activation
Authors: Kamalakshi Deka, Jean-Michel Carter, Akash Bahai, Daniel Aron Ang, Nicholas Sim, Hooi Yan Chong, Guan Hwee Bernard Lee, Suet Mien Tan, Wee Joo Chng, Dennis Kappei, Yinghui Li
You can read the Full Article in Nature Communications.
You can find more posts featuring Robert Orlowski on OncoDaily.
