Robert Orlowski, Deputy Chair of Lymphoma/Myeloma, Vice Chair of MM Research, and Florence Maude Thomas Cancer Research Professor at the University of Texas MD Anderson Cancer Center, shared a post on X:
“Myeloma Paper of the Day:
TREM1+CD10+ neutrophil subset is prevalent in focal lesions, demonstrates T-cell immunosuppressive effects, correlates with shorter OS, and targeted inhibition through CXCR2 blockade with standard anti-MM txs reduces tumor burden.”
Title: Deciphering neutrophil dynamics in the focal lesion tumor microenvironment to overcome immunosuppression in multiple myeloma
Authors: Joshua Rivera, Qi Yan, Saeed Daneshmandi, Romain Lannes, Eriko Katsuta, Jee Eun Choi, Prashant K. Singh, Ahmed Belal, Ronald Alberico, Ian Lund, Magan Schaefer, Hamza Hassan, Sarah Parker, Kenneth C. Anderson, Nikhil C. Munshi, Mehmet K. Samur, Philip L. McCarthy, Jens Hillengass, Hemn Mohammadpour
You can read the Full Article on Blood.
You can find more posts featuring Robert Orlowski on OncoDaily.
