Robert Orlowski, Deputy Chair of Lymphoma/Myeloma, Vice Chair of MM Research and Florence Maude Thomas Cancer Research Professor at the University of Texas MD Anderson Cancer Center, shared a post on X:
“Myeloma Paper of the Day: Age-related mesenchymal stromal cell senescence may be associated with progression from MGUS to myeloma, in part due to upregulated expression of BMP antagonist Gremlin1 in MSCs, which facilitates myeloma proliferation.”
Authors: Natalya Plakhova, Vasilios Panagopoulos, Melissa Cantley, Laura Trainor, Duncan Hewett, Sheila Stewart, Stan Gronthos, Andrew Zannettino, Krzysztof Mrozik, Kate Vandyke et al.
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