Robert Orlowski, Florence Maude Thomas Cancer Research Professor at the University of Texas MD Anderson Cancer Center, shared a post on X:

“Myeloma Paper of the Day: Lachnospiraceae-inactivated phosphatidyl choline from myeloma cells inhibits CD8 T cell fxn via Sb9 mRNA maturation and exosomal Sb9 production via LPA reduces GZMB expression by suppressing tumor TP53 UFMylation in T cells.”

“Microbiota-reprogrammed phosphatidylcholine inactivates cytotoxic CD8 T cells through UFMylation via exosomal SerpinB9 in multiple myeloma”

Authors: Wei Yan, Xue Shi, Yun Zhao, Xiaoyu Liu, Xueming Jia, Le Gao, Jiahe Yuan, Aijun Liao, Hiroshi Yasui, Xiaobin Wang, Xiaotian Wang, Rui Zhang and Huihan Wang.

Myeloma Paper of the Day, March 26th, suggested by Robert Orlowski

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