Robert Orlowski, Florence Maude Thomas Cancer Research Professor at the University of Texas MD Anderson Cancer Center, shared a post on X:

“Myeloma Paper of the Day: CD8 T cells with a transgenic TCR targeting a peptide derived from BOB1 in context of HLA-B*07:02 + a BCMA-targeting CAR enhances efficacy, but CAR-mediated target recognition may limit TCR-mediated target recognition.”

“CAR-mediated target recognition limits TCR-mediated target recognition of TCR- and CAR-dual-receptor-edited T cells”

Authors: Tassilo Wachsmann, Teuntje Poortvliet, Miranda Meeuwsen, Dennis Remst, Marijke Toes, Anne Wouters, Renate Hagedoorn, Frederik Falkenburg, and Mirjam Heemskerk.

Myeloma Paper of the Day, March 4th, suggested by Robert Orlowski

More posts featuring Robert Orlowski.