Gustavo Viani

Gustavo Viani: New Study on SBRT vs Conventional Radiotherapy for Painful Bone Metastases

Gustavo Viani, Associate Professor at Faculty of Medicine of Ribeirão Preto (FMRP), University of São Paulo (USP), shared a post on X:

“New Study on SBRT vs. Conventional RT for Painful Bone Metastases!

Study Objective
Compare the effectiveness of dose-escalated SBRT (20 Gy) vs. conventional RT (8 Gy) in achieving complete pain response for painful bone metastases

Methods
  • Design: Phase III RCT, single-blind
  •  Patients: 126 with ≤3 painful bone mets (pain score ≥2/10)
  •  Treatment: SBRT 20 Gy (single fraction) vs. conventional RT 8 Gy (single fraction).
  •  Primary Outcome: Complete pain response at 1 month (International Consensus)
Key Results
  •  1 month: SBRT 37% vs. RT 25% (P = .25)
  •  3 months: SBRT 33% vs. RT 24% (P = .32)
  • Per-protocol (3 months): SBRT 54% vs. RT 31% (P = .048)
SBRT did not improve complete response rates at 1 month”

Title: Dose-Escalated Stereotactic Versus Conventional Radiotherapy for Painful Bone Metastases (ROBOMET): A Multicenter, Patient-Blinded Randomized Clinical Trial

Authors: Carole Mercier, Charlotte Billiet, Katrien Vandecasteele, Geert De Kerf, Michaël Claessens, Steven Van Laere, Peter Vermeulen, Luc Dirix, Yolande Lievens, Dirk Verellen, Piet Dirix

You can read the Full Article on Journal of Clinical Oncology

Gustavo Viani

More posts featuring Gustavo Viani.

cancer Carole Mercier Charlotte Billiet Dirk Verellen Geert De Kerf Gustavo Viani Katrien Vandecasteele Luc Dirix Michaël Claessens OncoDaily Oncology Painful Bone Metastases Peter Vermeulen Piet Dirix ROBOMET Steven Van Laere Yolande Lievens