Diego A. Díaz García, Medical Oncologist , CEO and Founder at CánCare, shared an article on X:
“HER3: from understudy to key target.
Once overlooked, HER3 is now gaining ground in cancer therapy. New strategies including ADCs & bispecifics show promise—like FDA-approved Zenocutuzumab for NRG1+ NSCLC & pancreatic cancer.
This article offers an essential overview of:
- HER3 biology, mutations, and expression in tumors.
- Its role in therapy resistance and immune interactions.
- Emerging HER3-directed therapies and their potential across cancer types.”
Emerging importance of HER3 in tumorigenesis and cancer therapy.
Authors: Joan T. Garrett, Salomon Tendler, Wasim Feroz, Mary Kate Kilroy, Helena Yu.
You can read the Full Article on Journal of Nature Reviews Clinical Oncology.
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