Nieves Martinez Lago, Controversies in NEN

Nieves Martinez Lago: PEM in MSI and dMMR advanced solid tumors

Nieves Martinez Lago, Medical Oncologist at University Hospital Complex of Ferrol, shared an article by Aurelien Marabelle, et al. on X:

“PEM in MSI and dMMR advanced solid tumors: updated results KN-158 trial. 

Phase II KN-158. N=373:

  • ORR 33.8%.
  • DoR 63.2 mo, OS 19.8 mo, PFS 4 mo.
  • Grade ≥3 TRAEs: 13%.

Supports pembrolizumab use in MSI-H/dMMR solid tumors.”

Pembrolizumab in microsatellite-instability-high and mismatch-repair-deficient advanced solid tumors: updated results of the KEYNOTE-158 trial.

Authors: Aurelien Marabelle, et al.

Nieves Martinez Lago: PEM in MSI and dMMR advanced solid tumors