Aaron Goodman, Hematologist/Oncologist and an Associate Professor of Medicine at the University of California, shared a post on X:
“Mature B-cell Leukemias my favorite ddx!
Classify by CD5/CD10
CD5+/CD10-:
CLL = CD23+
Leukemic mantle cell = CD23-
CD5-/CD10-:
Hairy cell leukemia = CD11c+, CD123+, BRAF+
HCLv/PLL = CD11c+, CD123-, BRAF-
SMZL = HCV, del7q31, MYD88 (subset)
CD5-/CD10+: Leukemic follicular.”
