International Society of Liquid Biopsy (ISLB) shared a post on X about a paper by Emily Podany et al. published in JAMA Network Open:
“Racial Disparities in ctDNA Profiles and Targeted Therapy in Metastatic Breast Cancer.
Key Findings:
- Black patients had higher GATA3 and CCND2 mutations vs. White patients.
- Lower use of PI3K inhibitors in Black patients (5.9% vs. 28.8%), despite mutations.
- Shorter overall survival (OS) in Black patients, highlighting inequities.
- Barriers include clinical trial exclusion, socioeconomic factors and access gaps.
Equitable access to precision oncology and clinical trials is critical!”
Authors: Emily Podany, Lorenzo Foffano, Lorenzo Gerratana, Massimo Cristofanilli, Andrew Davis et al.
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