Jamie Blundell, Professor of Cancer Research at University of Cambridge, shared on X about a recent paper shared by Adriana V.A. Fonseca et al. published in bioRxiv:
“Delighted to share our latest on longitudinal methylation dynamics preceding cancer. Epigenetic signs of AML appear in blood decades before Dx. By brilliant Adriana Fonseca.
- Early cancer
- Methylation drivers
- Epimutation rates
- CpG lineage tracing”
Title: Methylation dynamics in the decades preceding acute myeloid leukaemia
Authors: Adriana V.A. Fonseca, Christopher Boniface, Caroline J. Watson, Samuel Hackett, Calum Gabbutt, Akemi D. Ramos-Yamasaki, Amanda B. Tan, Jose Montoya, Ruslan Strogantsev, Lars L. P. Hanssen, Yuexuan Zhang, Sophia Apostolidou, Aleksandra Gentry-Maharaj, Sadik Esener, Paul Spellman, Trevor Graham, Usha Menon, Hisham Mohammed, Jamie R. Blundell
Read an Insightful article featuring Leukemia on OncoDaily.
