Arndt Vogel, Head of the Center for Personalized Medicine, MHH at Hannover Medical School, shared a post on X about a recent article by Venkata Ramana Mallela et al. published in European Journal of Cancer:
“Shallow whole-genome sequencing of circulating tumour DNA predicts clinical outcomes to systemic therapy in HCC
- sWGS enables evaluation of ctDNA
- High TF and fragmentation associated with poor prognosis
- TF predicts progression-free survival independently
- promising prognostic biomarker”
Title: Shallow whole-genome sequencing of circulating tumour DNA predicts clinical outcomes to systemic therapy in advanced hepatocellular carcinoma
Authors: Venkata Ramana Mallela, Sultan N. Alharbi, Mathew Vithayathil, Caroline Ward, Rishi Patel, Rohini Sharma
Read the Full Article on European Journal of Cancer
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