Anirban Maitra, Professor at MD Anderson Cancer Center, shared a post on X:
“New preprint from Hemann lab
In vivo screening reveals cell-intrinsic mediators of solid tumor resistance to CAR T cell-therapy. CRISPR screens in Pancreatic Cancer model identifies Nrf2 hyperactivity as a sensitizer to CAR-T cell therapy.”
Title: In vivo screening reveals cell-intrinsic mediators of solid tumor resistance to CAR T cell-therapy
Authors: Julia Fröse, Charles A. Whittaker, Paul Leclerc, Evelyn Chen, Sean Doherty, Adam Langenbucher, Riley D. Hellinger, Daniel Goulet, Tuomas Tammela, Michael T. Hemann
Read the Full Article.
