Anirban Maitra, Director of the Sheikh Ahmed Pancreatic Cancer Research Center, shared a post on X about a recent paper by Janelle Montagne et al. published in iScience journal:

“New iScience journal paper from Johns Hopkins Kimmel Cancer Center generating an integrated single-cell RNA-seq and TCR-seq dataset from a 3-arm neoadjuvant pancreatic cancer platform trial, comparing GVAX vaccine, vaccine + aPD-1, and vaccine + aPD-1 + aCD137 agonist (Urelumab).”

“CD137 agonism enhances anti-PD1 induced activation of expanded CD8+ T cell clones in a neoadjuvant pancreatic cancer clinical trial”

Authors: Janelle Montagne, Jacob Mitchell, Joseph Tandurella, Elizabeth Jaffee, Lei Zheng, Elana Fertig.

Anirban Maitra: New paper from Johns Hopkins Kimmel Cancer Center on pancreatic cancer

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Anirban Maitra serves as a Professor of Pathology and Translational Molecular Pathology at UT MD Anderson Cancer Center. He directs the Sheikh Ahmed Pancreatic Cancer Research Center and is a Distinguished University Chair at Sheikh Khalifa Bin Zayed Al Nahyan.

He leads an NCI-funded laboratory dedicated to pancreatic cancer research, focusing on genetics and molecular pathology in human and mouse models. His research aims to advance early detection and interception strategies to enhance patient survival rates in pancreatic cancer.