International Nonproprietary Names

Raffaele Colombo: First ever dual payload ADC in the clinic

Raffaele Colombo, Associate Director of Medicinal Chemistry at Zymeworks, shared a post on X:

“First ever dual payload ADC in the clinic by Chengdu Kanghong Biotech! KH815, a dual-payload ADC targeting TROP2.

Payloads:
“Drug-T” and “Drug-E”

And one of the two payloads is definitely a topoisomerase I inhibitor.”

Raffaele Colombo: First ever dual payload ADC in the clinic

“First-In-Human Study in Participants with Advanced Solid Tumors”

 

cancer Chengdu Kanghong Biotech Drug-E Drug-T OncoDaily Oncology Raffaele Colombo