A recent paper by Emma Dann, EMBO post-doctoral fellow in the Pritchard Lab at Stanford University, was mentioned by Marios Georgakis, Emmy Noether Research Group Leader and Clinician at LMU Munich, on X:

“Beyond genomics, single-cell RNA sequencing also shows relevance for drug target selection.

Targets with

high expression in disease-relevant cell types or
cell-type overexpression in disease patients,

are more likely to proceed in clinical development.”

“Estimating the impact of single-cell RNA sequencing of human tissues on drug target validation”

Authors: Emma Dann, Erin Teeple, Rasa Elmentaite, Kerstin Meyer, Giorgio Gaglia, Frank Nestle, Virginia Savova, Emanuele de Rinaldis, Sarah Teichmann.

Single-cell RNA sequencing shows relevance for drug target selection

More posts about single-cell RNA sequencing.

Emma Dann is a computational biologist with expertise in analyzing single-cell genomics data. She is currently an EMBO postdoctoral fellow at the Pritchard Lab at Stanford University and the Gladstone Institutes, as well as a visiting fellow in the Marson Lab at the Gladstone Institutes.