The University of Manchester has uncovered a more efficient and sustainable way to make peptide-based medicines

The University of Manchester has uncovered a more efficient and sustainable way to make peptide-based medicines

Manchester Cancer Research Centre shared on X:

“New breakthrough research published in Nature Chemical Biology led by The University of Manchester has identified a more efficient and sustainable way to make peptide-based medicines, showing promising effectiveness in combating cancers.”

"Using our new ligase enzymes we can produce peptides with promising anti-cancer activity in a single process with excellent yields. Previously, these types of peptides were produced in much lower yields, by a very laborious 10-12 step chemical synthesis process. "By combining different ligases together in a single cascade reaction, we can make many different peptides." Quote from Prof. Jason Micklefield Lead Researcher, The University of Manchester

Source: Manchester Cancer Research Centre/X

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