Jason A. Mouabbi, Assistant Professor at MD Anderson Cancer Center, made the following post on X/Twitter:
“Exciting news! Another ADC promises to broaden the treatment horizon in HR+ metastatic breast cancer.
Questions swirling in my mind:
1. HER2-low dilemma: Dato-DXd or T-DXd first? Can sequential use with the same drug conjugate (Deruxtecan) yield promising results?
2. How to choose between Sacituzumab & Dato-DXd? Can we sequence them?
So many queries, so few answers!
Hoping for a prospective registry to track ADC sequencing and unveil solutions to these questions and more!”
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Source: Jason A. Mouabbi/Twitter