Yan Leyfman, Co-founder and Executive Director of MedNews Week, shared a post on X by Robert McFarland et al., published in NEJM.
“Hope Through Mitochondrial Donation.
A UK reproductive program offering pronuclear transfer (a form of mitochondrial donation) to women with pathogenic mtDNA variants has resulted in 8 healthy live births.
- All infants had no or low mtDNA heteroplasmy
- Minor postnatal issues were manageable and resolved
- Normal developmental progress observed in all children
This marks a major step forward in preventing transmission of mitochondrial disease and offering families new hope through advanced reproductive technologies.”
Title: Mitochondrial Donation in a Reproductive Care Pathway for mtDNA Disease
Authors: Robert McFarland, Louise A. Hyslop, Catherine Feeney, Rekha N. Pillai, Emma L. Blakely, Eilis Moody, Matthew Prior, Anita Devlin, Robert W. Taylor, Mary Herbert, Meenakshi Choudhary, Jane A. Stewart, and Douglass M. Turnbull
Read The Full Article at NEJM.
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