Thor Halfdanarson, Vice President at the North American Neuroendocrine Tumor Society, shared on X about recent paper by him as co-author, titled “Sarcomas arising in MEN1 patients: demonstrating LOH of the MEN1 locus and loss of menin expression” published on Springer Nature.
Authors: Rachel S. van Leeuwaarde, Thorvardur R. Halfdanarson, Shwetha M. Sudhakar, Ruud W. J. Meijers, Andrew L. Folpe, Lodewijk A. A. Brosens.
“Is sarcoma a potential manifestation of MEN1…? In this small case series, 5 patients with a MEN1 and a sarcoma are described and all had sarcomas loss of heterozygosity of the MEN1 gene and loss of expression of menin. Study based on clinic observation.”