Jeroen Dekervel, Medical doctor at UZ Leuven, shared a post on LinkedIn:
“New ESMO Podcast on Upper GI Cancers – Highlights in Biliary and Pancreatic Cancers from ASCO 2025
Exciting developments in upper GI oncology were presented at ASCO25, and we unpack them in our latest ESMO podcast. I had the pleasure of discussing the key pancreatic and biliary cancer trials with two expert colleagues:
- Prof. Dr. Arndt Vogel (Princess Margaret Cancer Centre, Toronto / Hannover Medical School)
- Dr. Florian Castet (Vall d’Hebron Institute of Oncology, Barcelona)
We cover:
- The CASSANDRA trial on neoadjuvant therapy in resectable PDAC
- PANOVA-3 and tumor-treating fields for locally advanced disease
- Elraglusib for metastatic PDAC – innovation meets caution
- The GAIN and POLCA-GB trials in resectable and locally advanced biliary tract cancer
We critically reflect on trial design, endpoints, toxicity, and what these results mean for clinical practice.