Angelo Pirozzi

Angelo Pirozzi: CAR-T cells targeting claudin18.2 in pretreated advanced PDAC by Changsong Qi et al.

Angelo Pirozzi, Medical Oncology Fellow at Humanitas University and Research Fellow at Mayo Clinic (Phoenix), made the following post on X:

”CAR-T cells targeting claudin-18.2 in pretreated advanced PDAC.

  • 2 phase I/Ib trials with 24 patients.
  • 79% ≥2 previous systemic lines.
  • ORR 16.7%.
  • DCR 70.8%.
  • mPFS 3.3 months.
  • mOS 10.0 months.
  • mDoR 9.5 months.”

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Source: Angelo Pirozzi/X

Angelo Pirozzi cancer CAR-T cells Chang Liu Changsong Qi Claudin-18.2 Daijing Yuan Dan Liu Jiajia Yuan Jian Li Jifang Gong Jun Zhang Jun Zhou Lin Shen Miao Zhang Ning Li OncoDaily Oncology Panpan Zhang PDAC Raffaele Baffa Xiaohui Peng Xiaotian Zhang Xicheng Wang Yumeng Wang Zhen Liu