Gertjan Rasschaert, Medical Doctor, Consultant Gastrointestinal Oncology and Gastroenterology at
“Botbal in refractory pMMR/MSS mCRC: a phase 1 trial
In the response-evaluable population (n = 101), ORR was 17% (95% CI 10–26%), DCR 61% (95% CI, 51–71%) and median PFS 3.5 months (95% CI, 2.7–4.1 months), at a median FU of 10.3 months.
A randomized phase 2 study of this combination is underway to confirm the comparative safety and efficacy of the BOT and BAL combination. With enthusiast participation of DIO UZ Leuven !
g is cooking in the age group of 20-49 years. Also the exact reason why just lowering the screening age to 45 years won’t suffice.”
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Source: Gertjan Rasschaert/X