Lumír Kunovský, shared a post by Sara Nikolić, GI fellow at UKC Maribor, on X, adding:
“November is Pancreatic cancer awarness month. Risk stratification of individuals with a germline CDKN2A pathogenic variant
Thanks for sharing Sara.
What’s New.
1 in 4 individuals with a germline CDKN2A pathogenic variant are expected to develop pancreatic cancer in their lifetime
Only in UEGJ.
Cumulative incidence of pancreatic ductal adenocarcinoma (PDAC; red) or death from other causes (blue).
Only in UEGJ.”
Quoting Sara Nikolić‘s post:
“Despite surveillance in carriers of a mutation CDKN2A, late stage and interval pancreatic cancer still occur
High risk:
– 1st-degree Pregnancy with PDAC
– Smoke history
Current model not reliable for clinical practice. Biomarkers.”
Authors: Derk C. F. Klatte, Jihane Meziani, Djuna L. Cahen, Merel van Diepen, Marco J. Bruno, Monique E. van Leerdam, the Dutch Pancreatic Cancer Surveillance Group
