Jens Puschhof, Principal Investigator at DKFZ German Cancer Research Center, posted on X:
“Bacteria cause mutations in cancer—but only if they stick to host cells. Brilliant study from Lars Vereecke lab in Nature.
Our accompanying perspective with Kyanna Ouyang.
Lots of implications for new CRC prevention approaches!
Congratulations to all authors of this beautiful work, especially 1st authors, Maude Jans, Magdalena Kolata, senior authors, Lars Vereecke, Han Remaut and everyone involved!”
Colibactin-driven colon cancer requires adhesin-mediated epithelial binding
Authors: Maude Jans, Magdalena Kolata, Gillian Blancke, Aline D’Hondt, Claudia Gräf, Maarten Ciers, Mozes Sze, Alexandra Thiran, Ioanna Petta, Vanessa Andries, Sara Verbandt, Engy Shokry, David Sumpton, Johan Vande Voorde, Geert Berx, Sabine Tejpar, Geert van Loo, Iliyan D. Iliev, Han Remaut & Lars Vereecke
Sticky situation: how adhesive bacteria drive colon cancer
Authors: Kyanna S. Ouyang & Jens Puschhof